{"id":1850,"date":"2025-11-11T09:00:29","date_gmt":"2025-11-11T14:00:29","guid":{"rendered":"https:\/\/tickle.utk.edu\/mse\/?p=1850"},"modified":"2026-04-08T13:13:23","modified_gmt":"2026-04-08T17:13:23","slug":"accelerated-discovery","status":"publish","type":"post","link":"https:\/\/tickle.utk.edu\/mse\/accelerated-discovery\/","title":{"rendered":"Accelerated Discovery"},"content":{"rendered":"<p class=\"lead\"><i>UT Positioned as Leader in Automated Characterization and Autonomous Processing<\/i><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"2250\" height=\"1250\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header.jpg\" alt=\"Gerd Duscher and grad students look inside the proton microscope at UT.\" class=\"alignnone size-full wp-image-1864\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header.jpg 2250w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header-300x167.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header-1024x569.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header-768x427.jpg 768w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header-1536x853.jpg 1536w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-Header-2048x1138.jpg 2048w\" sizes=\"auto, (max-width: 2250px) 100vw, 2250px\" \/><\/p>\n<p>Automated characterization is necessary to close the loop between synthesis and discovery of new materials. Through its award-winning faculty, state-of-the-art facilities, and location, the University of Tennessee is at the forefront of this transformative process.<\/p>\n<p>UT\u2019s framework serves as a model for how machine learning-driven automated materials discovery and scalable experimentation can shorten the path from concept to deployment, advancing the nation\u2019s competitiveness in\u00a0nuclear, aerospace, and advanced manufacturing technologies.<\/p>\n<p>UT is one of only three programs in the country that works on automated characterization, alongside <a href=\"https:\/\/www.ornl.gov\">Oak Ridge National Laboratory<\/a> (ORNL) and <a href=\"https:\/\/www.pnnl.gov\">Pacific Northwest National Laboratory<\/a> (PNNL). The practice accelerates the materials discovery and development process, which can be time consuming and expensive, by using automated hardware that can execute experiments, collect and analyze data, and interpret results.<\/p>\n<p>\u201cThese capabilities position UT as a leader in translating fundamental materials innovation into scalable, real-world applications,\u201d said <a href=\"https:\/\/tickle.utk.edu\/mse\/faculty\/mohsen-asle-zaeem\/\">Mohsen Asle Zaeem<\/a>, the department head of the Department of Materials Science and Engineering (MSE). \u201cThe integration of cloud-enabled microscopy, automated synthesis, and high-performance computing directly supports the development of next-generation materials for\u00a0nuclear energy systems,\u00a0aerospace structures and systems, and\u00a0national defense.\u201d<\/p>\n<p>As one of the first institutions in the US to work on high-throughput automated synthesis and characterization, UT is helping advance the capabilities of AI materials discovery while training the next generation of the workforce, scientists, and engineers.<\/p>\n<p>\u201cIt doesn&#8217;t matter how much stuff you make if you cannot characterize it,\u201d said MSE Weston Fulton Professor <a href=\"https:\/\/tickle.utk.edu\/mse\/faculty\/sergei-kalinin\/\">Sergei Kalinin<\/a>. \u201cCharacterization is the missing link from the accelerated material discovery in the future. The unique piece of UT is being the place where the accelerated characterization is being done.\u201d<\/p>\n<h2 class=\"h3 orange-mark\">Bringing AI to the Labs<\/h2>\n<p>UT has a long tradition of excellence in the field of materials characterization, spearheaded by faculty members like MSE Professor <a href=\"https:\/\/tickle.utk.edu\/mse\/faculty\/gerd-duscher\/\">Gerd Duscher<\/a> and <a href=\"https:\/\/cee.utk.edu\/people\/dayakar-penumadu\">Dayakar Penumadu<\/a>, the Fred N. Peebles Professor and IAMM Chair of Excellence.<\/p>\n<p>Currently, UT is the only academic institution that has built fully cloudified electron and scanning probe microscopy and nanoindentation. These instruments can stream imaging data to the cloud, analyze it, and return control commands back to the instrument. This enables the bridge between the ML-agents and real-world instrumentation, opening the door to the ML algorithms to act on the nanometer and atomic scales.<\/p>\n<p>UT is also home to one of the first automated high throughput synthesis labs in the country, directed by Associate Professor <a href=\"https:\/\/tickle.utk.edu\/mse\/faculty\/mahshid-ahmadi\/\">Mahshid Ahmadi<\/a>, and combinatorial research labs, directed by <a href=\"https:\/\/tickle.utk.edu\/mse\/faculty\/philip-rack\/\">Philip Rack<\/a>, MSE professor, Leonard G. Penland Chair, and Director of the Center for Materials Processing (CMP).<\/p>\n<div style=\"margin: 40px 0px\">\n<div class=\"responsive-container\"><iframe loading=\"lazy\" title=\"Accelerating Materials Discovery\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/1Q5zk7tlYe4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<\/div>\n<p>\u201cThe uniqueness of our approach at UT is that we always start bottom up and not the top down,\u201d Kalinin said. \u201cWe don&#8217;t come up with the idealized suggestion, and try to squeeze it into real world, which is the reason why things seldom work for machine learning in real world applications. What we try to do is start with the real tools in the lab and make them faster, make them talk to each other faster, make them solve the problems faster.&#8221;<\/p>\n<p>Ahmadi has been working at the intersection of AI and autonomous material synthesis and characterization since 2019 and is one of the pioneers in adapting self-driving labs (SDLs) trying to harness the power of SDL technologies to revolutionize the approach to the world\u2019s energy challenges.<\/p>\n<p>Her lab in the <a href=\"https:\/\/research.utk.edu\/iamm\">Institute of Advanced Materials and Manufacturing<\/a> (IAMM) houses three liquid handling robots capable of printing optoelectronic materials, as well as a fully automated spin bot system capable of spin coating 10 films and perform in-situ characterization of optoelectronic materials, all integrated with large language model (LLM) agents. These uniquely developed tools are not only essential for understanding how materials grow and crystallize but also enable unprecedented insights into their fundamental properties.<\/p>\n<p>\u201cIt\u2019s one of the most unique labs in the nation that is fully automated,\u201d said Ahmadi, who focuses on materials for energy and solar application. \u201cWe&#8217;re now capable of integrating LLM agents and the use of ML for decision making to help us close the loop of hypothesis formation, experimental planning, data analysis and provide the feedback in the loop and then do a much more intelligent decision making in order to optimize or discover materials.\u201d<\/p>\n<h2 class=\"h3 orange-mark\">Uniquely Positioned for Innovation<\/h2>\n<p>UT\u2019s microscopy facilities at IAMM are all combined to have a uniform platform so that machine learning tools can be deployed to all of them. Among the tools are automated microscopes, scanning probe microscopes, electron microscopes, ion microscopes, and a transmission electron microscope that has a resolution of 42 picometers&#8211;approximately one trillionth of a meter.<\/p>\n<p>The transmission electron microscope is controlled by a supercomputer. The facility is also planning to control the scanning electron microscope and focused ion beam microscope with the same platform and machine learning tools.<\/p>\n<p>\u201cThe supercomputer takes images and looks at various specific features in that image. Then, you can jump around depending on what you find of interest,\u201d said Duscher, whose research areas includes atomic and electronic structure on the atomic level. \u201cThat means that you are concentrating more on scientific questions instead of the operation of the instrument. The performance is much quicker and efficient, because the machine is often much quicker to select specific points of and characterize under very small areas on a large sample.\u201d<\/p>\n<p>Through the university\u2019s support and faculty expertise, Duscher believes UT is ideally suited to take advantage of the resources.<\/p>\n<p>\u201cThe key thing is we not only have these instruments, but we also have the environment for these microscopes to operate all this up to their specifications,\u201d Duscher said. \u201cThe facilities we have at UT are extremely good and, combined with the knowledge we have here in the area, we are very uniquely positioned to do microscopy and machine learning together on a world-class level.\u201d<\/p>\n<h2 class=\"h3 orange-mark\">Accelerating Future Discovery<\/h2>\n<p>The infrastructure in place at UT enhances its position as a national hub for advanced materials research and innovation.<\/p>\n<p>\u201cThe collaboration between UT, ORNL, and\u00a0local and statewide industry partners is driving economic and workforce development across East Tennessee and the broader state,\u201d Asle Zaeem said. \u201cThese efforts directly support Tennessee\u2019s priorities in technology-based growth, manufacturing competitiveness, and energy security.\u201d<\/p>\n<p>The research being performed at UT can lead to the discovery of new materials and possibly change the properties of known materials for new applications. The impact spans from lightweight alloys for aircraft engines to heat shields of spacecrafts to quantum sensors.<\/p>\n<p>Before the current push to integrate AI into materials discovery, UT had the foresight that transformation was necessary to spark innovation.<\/p>\n<p>\u201cMaterials science doesn\u2019t usually change over time. But now it\u2019s a different time. I can even say that it&#8217;s the inflection point,\u201d Ahmadi said. \u201cWe started, we learned from the history, and we had this vision early on. Being <span class=\"NormalTextRun SCXW173968868 BCX0\" data-ccp-parastyle=\"Normal (Web)\">early is<\/span> <span class=\"NormalTextRun SCXW173968868 BCX0\" data-ccp-parastyle=\"Normal (Web)\">very<\/span> <span class=\"NormalTextRun SCXW173968868 BCX0\" data-ccp-parastyle=\"Normal (Web)\">important<\/span><span class=\"NormalTextRun SCXW173968868 BCX0\" data-ccp-parastyle=\"Normal (Web)\"> because we have gained knowledge through experience and are close to tackling all the challenges.\u201d<\/span><\/p>\n<h2 class=\"h3 orange-mark\">Photo Gallery<\/h2>\n<p>Check out some photos of our researchers using materials research facilities inside the Institute for Advanced Materials and Manufacturing.<\/p>\n<div id='gallery-1' class='gallery galleryid-1850 gallery-columns-2 gallery-size-full'><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00007.jpg\" class=\"attachment-full size-full\" alt=\"Gerd Duscher looks in on the electron microscope.\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00007.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00007-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00007-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00007-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00008.jpg\" class=\"attachment-full size-full\" alt=\"Gerd Duscher speaks with two UT researchers concerning the electron microscope at IAMM\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00008.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00008-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00008-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00008-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><br style=\"clear: both\" \/><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00006.jpg\" class=\"attachment-full size-full\" alt=\"UT researcher looks in on the electron microscope in the IAMM Microscopy Lab\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00006.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00006-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00006-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00006-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00001.jpg\" class=\"attachment-full size-full\" alt=\"Two UT researchers review images from the electron microscope.\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00001.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00001-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00001-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00001-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><br style=\"clear: both\" \/><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00005.jpg\" class=\"attachment-full size-full\" alt=\"Mahshid Ahmadi works with two UT grad students with automated spin bot in a materials synthesis lab.\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00005.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00005-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00005-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00005-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00002.jpg\" class=\"attachment-full size-full\" alt=\"Student works with sample inside material synthesis lab\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00002.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00002-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00002-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00002-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><br style=\"clear: both\" \/><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00004.jpg\" class=\"attachment-full size-full\" alt=\"UT student researcher works with a liquid handling robot creating samples in one of UT&#039;s materials synthesis labs.\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00004.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00004-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00004-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00004-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><dl class='gallery-item'>\n\t\t\t<dt class='gallery-icon landscape'>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1000\" src=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00003.jpg\" class=\"attachment-full size-full\" alt=\"UT student researcher launches liquid handling robot to create samples in a UT materials synthesis lab.\" srcset=\"https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00003.jpg 1500w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00003-300x200.jpg 300w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00003-1024x683.jpg 1024w, https:\/\/tickle.utk.edu\/mse\/wp-content\/uploads\/sites\/2\/2025\/11\/Accelerated-Discovery-00003-768x512.jpg 768w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n\t\t\t<\/dt><\/dl><br style=\"clear: both\" \/>\n\t\t<\/div>\n\n<h2 class=\"h4 orange-mark\">Contact<\/h2>\n<p>Rhiannon Potkey (<a href=\"mailto:rpotkey@utk.edu\">rpotkey@utk.edu<\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Led by the Department of Materials Science and Engineering, UT is at the forefront of using machine-learning in the materials discovery process.<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[3,384,4],"tags":[392,413,51,7],"class_list":["post-1850","post","type-post","status-publish","format-standard","hentry","category-faculty","category-press-releases","category-research","tag-gerd-duscher","tag-iamm","tag-mahshid-ahmadi","tag-ornl"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Accelerated Discovery - Materials Science and Engineering<\/title>\n<meta name=\"description\" content=\"Led by materials science and 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